Project: DisPersal of AntIbiotic Resistance and antibiotics in Water ecosystems and Influence on liveStock and aquatic wildlife
| Acronym | PAIRWISE (Reference Number: ID 76) |
| Duration | 01/09/2021 - 31/08/2024 |
| Project Topic | PAIRWISE aims to advance knowledge of antimicrobial resistance (AMR) as a pollution in aquatic environments, wildlife, and livestock. PAIRWISE focuses on dispersal and dynamics of antibiotic resistant bacteria (ARB), antibiotic resistance genes (ARG) and antibiotics (ATB) in aquatic environments affected by wastewater treatment plants (WWTPs). Overall goals are to understand: i)dispersal of ARB, ARG and ATB in surface waters downstream of WWTPs, ii)carriage of ARB and ARG in livestock linked to surface waters influenced by WWTPs, iii)role of aquatic birds in dispersal of ARB and ARG. Issues from the JPI call tackled by PAIRWISE include, but are not limited to: entry points and fate of ARB, ARG and ATB; identification of ARGs and ARB useful as indicators; providing insight to fate and transport of ARB, ARG and ATB to within and from aquatic ecosystems; and the role of aquatic birds in such events. PAIRWISE will assess the influence of AMR in agricultural settings and improve understanding of the dissemination and sustainment of AMR in the interface between humans, wildlife, and livestock with a ‘One Health’ perspective. It will provide vital knowledge for policy makers and end-users, facilitating informed decisions on mitigation strategies. |
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Project Results (after finalisation) |
The overall aim of PAIRWISE is to provide insight into the dispersal of ATB, ARB and ARG downstream of WWTPs by comparing different geographical/climatic regions, wastewater management practices and types of water bodies. PAIRWISE will also investigate the potential influence that WWTPs have on occurrence of ARB and ARG in livestock downstream of the WWTPs. Furthermore, by combining state-of-the-art phenotypic and molecular methodologies together with high-resolution telemetry data on animal movements, PAIRWISE will obtain ground-breaking knowledge about how different point-sources affect occurrence in aquatic birds, and the role birds play in transfer of pollutants between aquatic habitats, regionally and between countries and continents. With the involvement of several key stakeholders and associated partners together with a plan of effective dissemination of our results, PAIRWISE provides novel and necessary tools needed to facilitate the formation of potential mitigation strategies for environmental dissemination of ARB, ARG and ATB. |
| Network | AquaticPollutants |
| Call | 1st AquaticPollutants Joint Call 2020 |
Project partner
| Number | Name | Role | Country |
|---|---|---|---|
| 1 | National Veterinary Insitute (SVA) | Coordinator | Sweden |
| 2 | Norwegian Institute for Water Research (NIVA) | Partner | Norway |
| 3 | Linköping University (LiU) | Partner | Sweden |
| 4 | Estación Biológica de Doñana, Consejo Superior de Investigaciones Cientificas (EBD-CSIC) | Partner | Spain |
| 5 | National Research Institute for Rural Engineering, Water, and Forestry (INRGREF) | Partner | Tunisia |
| 6 | Faculty of medicine Ibn Al-Jazzar Sousse (FMS) | Partner | Tunisia |
| 7 | Makerere University (MAK) | Partner | Uganda |