Project: Traceability for biologically relevant molecules and entities
Accurate counting of biological entities such as DNA and cells is vital for the security, healthcare and food sectors, among others. Specific applications include the monitoring of tumour cells in patients, the detection of genetically modified organisms in food and the quality control of tissue engineered products. This project will use purified calibration materials and counting technologies for biological measurements to bring traceable measurement to biology. It will develop methods to characterise pure biological materials for calibration, while establishing procedures for primary reference measurements of amount of nucleic acid based on single-molecule detection and counting, using digital PCR (polymerase chain reaction). The project will also focus on monitoring for minimal residual disease, as used in the treatment of leukaemia to determine whether the therapy is successful. The results will reduce some of the most important barriers to the adoption of SI traceability for a wide range of biological measurements.
| Acronym | SIB54 Bio-SITrace (Reference Number: SIB54) |
| Duration | 01/07/2013 - 30/06/2016 |
| Project Topic | Metrology |
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Project Results (after finalisation) |
See Website |
| Website | visit project website |
| Network | EMRP |
| Call | EMRP Call 2012 - Industry, SI Broader Scope and Open Excellence |
Project partner
| Number | Name | Role | Country |
|---|---|---|---|
| 1 | LGC Limited | Coordinator | United Kingdom |
| 2 | Istituto Nazionale di Ricerca Metrologica | Partner | Italy |
| 3 | Laboratoire national de métrologie et d'essais | Partner | France |
| 4 | Nacionalni Institut za Biologijo | Partner | Slovenia |
| 5 | Physikalisch-Technische Bundesanstalt | Partner | Germany |
| 6 | Turkiye Bilimsel ve Teknolojik Arastirma Kurumu | Partner | Türkiye |