Project: Innovative Technological Approaches for validation of Salivary AGEs as novel biomarkers in evaluation of risk factors in diet-related diseases

WHAT: Recent findings convincingly demonstrate that Advanced Glycation End Products (AGEs) are modifiable by diet and reflect changes in healthy state. SALIVAGES will investigate whether that diet-induced AGEs can act as reliable biomarkers of changes in health status and/or risk, focusing on the most highly accessible source of AGEs, the saliva. WHO: The project is proposed by a highly qualified multidisciplinary research team with complementary experience in different fields of biochemistry, pathology, pharmacology and analytical chemistry. The scientific network involves five different European countries: ITALY (Massimo Collino, University of Turin), SPAIN (Rosa M. Sainz, University of Oviedo), IRELAND (Lokesh Joshi, National University of Ireland Galway), ROMANIA (Ilea Aranka, University of Cluj-Napoca), GERMANY (Thomas Henle, Technische Universität Dresden). HOW: SALIVAGES will provide innovative and original tools for assessing status and efficacy of interventions, namely biosensors, metabolomics and biomimic approaches. It will also deepen our understanding of the early events leading to the changes in health status, by multidisciplinary approaches based on the integration of preclinical biological and molecular studies, analytical and food chemistry, information technologies, and glycomic analyses.

Acronym	SALIVAGES (Reference Number: 566)
Duration	01/03/2017 - 01/03/2020
Network	ERA-HDHL
Call	Call for Joint Transnational Research Proposals: Biomarkers for Nutrition and Health

Project partner

Number	Name	Role	Country
1	University of Turin	Coordinator	Italy
2	University of Medicine and Pharmacy Iuliu Hatieganu Cluj	Partner	Romania
3	University of Oviedo	Partner	Spain
4	National Centre for Biomedical Engineering Science, Biomedical Sciences	Partner	Ireland
5	Faculty of Science, Technische Universitaet Dresden	Partner	Germany