Project: HepaPlateTM – High throughput Organ-on-a-Chip model for Liver Toxicity Screening
We will develop an Organ-on-a-Chip hepatotoxicity-screening platform for toxicological evaluation of small molecules (Annex A). This innovative, high throughput approach combines Medicyte’s unlimited source of upcyte® Cells and MIMETAS OrganoPlates™ (Annex C). The liver model will consist of 3D hepatocyte organoids with sinusoidal endothelial and immune cells (Annex B). The HepaPlate™ will be validated for a compound library with known hepatotoxicity profiles.
| Acronym | HepaPlateTM (Reference Number: 9804) |
| Duration | 01/09/2015 - 01/09/2017 |
| Project Topic | Biological Sciences / Technologies |
| Network | Eurostars 2 |
| Call | Eurostars Cut-Off 3 |
Project partner
| Number | Name | Role | Country |
|---|---|---|---|
| 21845 | MIMETAS | Coordinator | Netherlands |
| 21846 | Medicyte GmbH | Partner | Germany |