Project: In-joint application of non-viral mRNA therapy for osteoarthritis
| Acronym | JOINT-APPROACH (Reference Number: 12792) |
| Duration | 01/05/2019 - 03/05/2022 |
| Project Topic | We will develop a novel safe (non-viral) and effective gene therapy-like mRNA therapy for osteoarthritis (OA). Using unique in-joint injectable polymer-based nanoparticle carriers, intracellular delivery of mRNA into joint-related tissues can be ensured. This therapy will suppress inflammation and support cartilage and tendon tissue regeneration. The project will perform the preclinical development to generate proof-of-concept, required for subsequent regulatory pre- and clinical validation. |
| Network | Eurostars 2 |
| Call | Eurostars Cut–off 10 |
Project partner
| Number | Name | Role | Country |
|---|---|---|---|
| 1 | 20Med Therapeutics BV | Coordinator | Netherlands |
| 2 | Ethris GmbH | Partner | Germany |
| 3 | AO Research Institute Davos | Partner | Switzerland |
| 4 | Paracelsus Medical University | Partner | Austria |