Project: Discover RNA-targeting drugs by NMR automation

Acronym	DiscoveRNA (Reference Number: 115328)
Duration	01/01/2022 - 01/01/2025
Project Topic	We will establish an automated pipeline enabling structure-based drug discovery (SBDD) using NMR for RNA targets. We will deliver optimized software capable of using a priori knowledge of a 3D RNA structure and a minimal number of NMR experiments to determine the structure of RNA–ligand complexes. Machine learning-based NMR spectrum analysis will be the disruptive technology. The automated workflow will yield complex structures fast enough to seamlessly integrate them into the SBDD process.
Network	Eurostars 2
Call	Eurostars Cut–off 15

Project partner

Number	Name	Role	Country
1	Eidgenössische Technische Hochschule Zürich	Partner	Switzerland
2	ZoBio B.V.	Coordinator	Netherlands