Project: Functional oxygen affinity measurement under shear for follow-up of sickle cell disease patients

Acronym Shearox (Reference Number: 115561)
Duration 01/10/2021 - 01/10/2024
Project Topic A novel instrument and method will be developed to rapidly determine the oxygen affinity of hemoglobin in patients with hereditary hemolytic anemias (HHA). This method will mimic physiological conditions by measuring the oxygen hemoglobin dissociation curve (ODC) in red blood cells (RBCs) during shear stress (Shearox measurement). Based on such an ODC measurement, personalized treatment can be developed for patients with HHA to enhance their quality of life and reduce costs of treatment.
Network Eurostars 2
Call Eurostars Cut–off 15

Project partner

Number Name Role Country
1 R&R Mechatronics International B.V. Coordinator Netherlands
2 Rigshospitalet Partner Denmark
3 Universitair Medisch Centrum Utrecht Partner Netherlands