Project: Flavodoxin inhibitors to kill resistant bacteria

Acronym	FLAV4AMR (Reference Number: JPIAMR_2018_P005)
Duration	01/01/2019 - 31/12/2021
Project Topic	This transnational collaboration gathers the expertise and resources required to address lead improvement to the point of producing novel antibiotics ready for clinical trials, and to clarify the overall importance of flavodoxin as a novel drug target. The project has two goals: 1. To culminate the improvement of inhibitors of the flavodoxin from H. pylori, which have shown efficacy against reference and clinical strains (including a clarithromycin-resistant one) and in a mice model. 2. To determine the relevance of flavodoxin as a novel drug target to fight bacteria which pose problems associated to antimicrobial resistance.
Website	visit project website
Network	JPI AMR
Call	6th Joint Call of JPIAMR

Project partner

Number	Name	Role	Country
1	University of Zaragoza	Coordinator	Spain
2	Pasteur Institute	Partner	France
3	Research Center Borstel	Partner	Germany
4	Ecole Nationale Vétérinaire de Toulouse	Partner	France