Project: International Research Alliance for Antibiotic Discovery and Development

Acronym	IRAADD (Reference Number: JPIAMR_2018_N025)
Duration	01/01/2019 - 31/03/2021
Project Topic	The IRAADD network includes internationally renowned groups with excellent records of accomplishment in AMR research focussing on early stages of antibiotic discovery and development. This expert team will include natural products researchers, medical microbiologists, bioinformaticians, medicinal chemists and target-based drug designers, as well advisory partners from global alliances focussing on antibiotic development such as DNDi/GARDP and IMI-ENABLE. The partners of the network will set up a cooperative platform that will allow the sharing of scientific research data, translational knowledge and expert advice for the strategic development of new and advanced projects with the aim to take collaborative scientific research in the early stages of antibiotics discovery and development to a new level. IRAADD believes that such an integrative research network with international outreach will be an important step forward to close the gap in translational drug development, which has been lasting for several decades. IRAADD will represent a consortium of leaders from academia and other sectors who will actively address the worldwide concern of spreading AMR. While this crisis is steadily expanding, research and development of novel antibiotics is inhibited because of underfinanced discovery and development projects prior to the preclinical trial phase, which are essential to provide new and innovative antibiotics for saving patient lives today and in future. In addition, there is currently no network available to leverage the ideas and projects of academic groups, which typically do not move forward towards application. Thus, our initiative aligns with the current “One Health Action Plan against Antimicrobial Resistance” introduced by the European Commission, which explicitly demands the implementation and support of “research into the development of new antimicrobials” and the establishment of sustainable research networks in this area. However, IRAADD strongly believes that the current situation and available institutions do not efficiently allow for a coordination and coaching especially of academic partners regarding translation of urgently required research on novel antibiotics into clinical use.
Website	visit project website
Network	JPI AMR
Call	8th Joint Call of JPIAMR

Project partner

Number	Name	Role	Country
1	Helmholtz Centre for Infection Research	Coordinator	Germany
2	Shandong University	Observer	China
3	Technical University of Denmark	Observer	Denmark
4	Pasteur Institute	Observer	France
5	Université de Lorraine	Observer	France
6	University of Lorraine	Observer	France
7	Université Paris-Saclay	Observer	France
8	French National Museum of Natural History	Observer	France
9	Pasteur Institute	Observer	France
10	University of Strasbourg	Observer	France
11	University of Tübingen	Observer	Germany
12	University of Frankfurt	Observer	Germany
13	Bielefeld University	Observer	Germany
14	Helmholtz Centre for Infection Research	Observer	Germany
15	Bonn University Medical Center	Observer	Germany
16	Saarland University	Observer	Germany
17	University of Bonn	Observer	Germany
18	University of Tübingen	Observer	Germany
19	University of Perugia	Observer	Italy
20	NAICONS Srl	Observer	Italy
22	University of Parma	Observer	Italy
23	Leiden University	Observer	Netherlands
24	AMR Insights	Observer	Netherlands
25	Wageningen University & Research	Observer	Netherlands
26	Polish Academy of Sciences	Observer	Poland
27	University of Lisbon	Observer	Portugal
28	University of Ljubljana	Observer	Slovenia
29	University of Cape Town	Observer	South Africa
30	Fundación MEDINA	Observer	Spain
31	Uppsala University	Observer	Sweden
32	ETH Zurich	Observer	Switzerland
33	University of Bern	Observer	Switzerland
34	University of Manchester	Observer	United Kingdom
35	John Innes Centre	Observer	United Kingdom
36	University of Dundee	Observer	United Kingdom
37	University Hospital Tübingen	Observer	Germany