Understanding the mechanisms of non-pharmacological interventions
Basic Information
Neurodegenerative diseases are debilitating and largely untreatable conditions that are strongly linked with age. Worldwide, there are estimated to be 50 million people with Alzheimer’s disease and related disorders, the most common group of neurodegenerative diseases. This figure is expected to double every 20 years as the population ages. The total direct and informal care costs of Alzheimer’s, Parkinson’s and related disorders are expected to surpass €350 billion per year across the European Union. Existing treatments for neurodegenerative diseases are limited in effect and mainly address the symptoms rather than the cause or the progressive course. In this context, the EU Joint Programme - Neurodegenerative Disease Research (JPND) has been established to better coordinate research efforts across countries and disciplines to more rapidly find causes, develop cures and identify better ways to care for people with neurodegenerative diseases.
| Network | JPND | ||||||||
| Website | https://www.neurodegenerationresearch.eu/initiatives/annual-calls-for-proposals/closed-calls/understanding-the-mechanisms-of-non-pharmacological-interventions/ | ||||||||
| Aim of the joint call | The aim of the call is to establish a number of ambitious, innovative, multi-disciplinary and multi-national collaborative research projects that aim at understanding the biomedical, psychological and/or social mechanisms of non-pharmaceutical interventions in order to identify potential target sites for enhanced personalized interventions or a combination of pharmacological and non-pharmacological interventions. Proposals must focus on one or several of the following neurodegenerative diseases: • Alzheimer’s disease and other dementias • Parkinson’s disease and PD‐related disorders • Prion diseases • Motor neuron diseases • Huntington’s disease • Spinocerebellar ataxia (SCA) • Spinal muscular atrophy (SMA) | ||||||||
| Type of joint call | Two Stages - Call with pre-proposals and full proposals submissions | ||||||||
| Events |
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| Is call co-funded? | No | ||||||||
| Call follow up funding | n/a | ||||||||
| Call reasons | n/a | ||||||||
| Research fields |
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| Type of research | n/a | ||||||||
| Target groups | n/a | ||||||||
| Participating networks | n/a |
Organisations Participating
Funded Projects
| Acronym | Title | Start | End | No. partners |
|---|---|---|---|---|
| AD_Imprint | Unlock the early life pathological imprinting of Alzheimer's... | 5 | ||
| AUTOFUS | Facilitating focused ultrasound-mediated Tau clearance in Al... | 5 | ||
| DC4MND | Multidimensional mechanistic investigations of trans spinal ... | 6 | ||
| EPI-3E | Defining (sex and age) cell-specific epigenetic mechanisms u... | 7 | ||
| EXERBRAIN | Crosstalk between exercise and brain lipid metabolism in the... | 3 | ||
| Good Vibes | Preventing Alzheimer's disease conversion by monitored vibra... | 5 | ||
| HiCALS | Hypothalamic mechanisms of High-Calorie intervention in ALS | 5 | ||
| Multi-MeMo | Shorter- and longer-term mechanisms of multimodal interventi... | 6 | ||
| NEURODIET | Molecular Mechanisms of Dietary Intervention on Neurodegener... | 5 | ||
| REBALANCE | Mechanisms of focused ultRasound mEdiated BrAin cLeAniNg Cou... | 6 | ||
| RECAST | Rebalancing sleep-wake disturbances in Parkinson's Disease w... | 6 | ||
| StepuP | Steps against the burden of Parkinson’s Disease | 6 | ||
| TREMENDOS | The role of microglia in the effects of environmental enrich... | 5 | ||
| UNITE-PD | Unraveling the Neural mechanisms underlying compensation str... | 4 |