Project: Functional Amyloid Chimera for Marine Biosensing

Acronym	FLAshMoB (Reference Number: MarTERA-2017_05)
Duration	01/05/2018 - 30/04/2021
Project Topic	The aim is to develop small, portable, easy to use, and robust biosensor platforms to monitor marine contaminants with high sensitivity and specificity, offering the ability to work on site and in a wide range of matrices. The bases for the development of the miniaturized sensors are chimera proteins endowed with both the adhesive properties of a self-assembling amyloid moiety and the recognition ability of specific proteins, such as: 1. laccase, an oxidative enzyme useful for sensing aromatic pollutants, polycyclic aromatic hydrocarbons and endocrine disrupting chemicals 2. Arsenate reductase, an extremophilic enzyme to be used for specific arsenic detection 3. Antibodies against marine toxins from algae, such as saxitoxin and domoic acid 4. Glutathione S-transferase (GST), a multifunctional protein useful for the detection of the total heavy metals content.
Website	visit project website
Network	MarTERA
Call	MarTERA ERA-NET Cofund

Project partner

Number	Name	Role	Country
1	University of Naples Federico II	Coordinator	Italy
2	CNRS/University of Grenobles Alpes	Partner	France
3	KLEARIA	Partner	France
4	Dropsens S.L.	Partner	Spain