Project: The activity-driven ER-mitochondria Calcium Cycle (ERMCC) and protein misfolding in neurodegenerative diseases: finding targets for therapy

Neurodegenerative diseases like Amyotrophic Lateral sclerosis and Alzheimer’s disease occur mostly without identifyable cause, and are as yet uncurable. The project aims to develop a new strategy of neuroprotection by moderation of the endoplasmic-reticulum-mitochondria-calcium cycle (ERMCC) which links functional and structural metabolism in neurons and plays a central role in neuronal development and survival.

Acronym	ERMCC-NDEG
Duration	01/03/2009 - 29/02/2012
Network	NEURON
Call	NEURON-2008 Neurodegeneration

Project partner

Number	Name	Role	Country
1	Friedrich-Schiller-University Jena	Coordinator	Germany
2	University of Goettingen	Partner	Germany
3	Fondazione S. Luca IRCCS	Partner	Italy
4	University of Valladolid	Partner	Spain