Project: The activity-driven ER-mitochondria Calcium Cycle (ERMCC) and protein misfolding in neurodegenerative diseases: finding targets for therapy
Neurodegenerative diseases like Amyotrophic Lateral sclerosis and Alzheimer’s disease occur mostly without identifyable cause, and are as yet uncurable. The project aims to develop a new strategy of neuroprotection by moderation of the endoplasmic-reticulum-mitochondria-calcium cycle (ERMCC) which links functional and structural metabolism in neurons and plays a central role in neuronal development and survival.
Acronym | FamPD |
Duration | 27/01/2009 - 26/01/2012 |
Network | NEURON |
Call | NEURON-2008 Neurodegeneration |